March 3-7, 2025 is Obesity care week.
The term «microdosis» probably makes you think of psychedelic drugs, we too. But the last trend in microdosis implies taking small amounts of popular weight loss medications known as LPG-1.
GLP-1 medications have revolutionized the way we treat diabetes and type 2 obesity. Injectable medications mimic a hormone made in the intestine called peptide-1 similar to glucagon (GLP-1), which helps control blood sugar, reduce the appetite and slow empty of the stomach so that it feels more full, longer.
Although GLP-1 medications have existed for decades as diabetes medications, they have only been approved for weight loss by the Federal Medicines Administration (FDA), and that is what has led to a significant increase in popularity and an increase in microdosis.
Glp-1 medications and microdosis
Microdesis medications GLP-1 means drinking smaller doses than are standard or recommended by the manufacturer.
Microdosan people for different reasons. On the one hand, the recent demand for GLP-1 medications has created current supply problems, and some microdosis people to help expand their supply.
The shortage of medicines can be particularly worrying for people in LPG-1 taking into account that investigation It shows that people who stop taking certain LPG-1 probably recover weight without the medication.
Microdosis LPG-1 has also been making rounds in social networks as a way to reduce the cost of medicines.
GLP-1 medications are not cheap. The price varies according to insurance, if you have insurance, and what LPG-1 prescribes you. But as a reference, most GLP-1 medications cost more than $ 1,000 per month without insurance.
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In addition to supply and cost, Fátima Cody Stanford, MD, MPH, MPAAssociate Professor of Medicine and Pediatrics at the Harvard Medicine School and Medicine of Obesity-Scientist Medicine Medicine at the weight center of Massachusetts General Hospital, said that the reasons for microdosis may include:
- Minimize possible side effects (nausea, vomiting, diarrhea) that can occur at higher doses
- To gradually use the body to medication before increasing to a complete therapeutic dose
- Experiment with the effects of medication on appetite and weight loss with lower doses
Does the MPS-1 microphone work?
For some people, medicines for LPG-1 microdeosos can work for their health objectives. According to Holly F. Lofton, MD, director of the Nyu Langone Health Medical Weight Management Program and member of the Healthywomen Women’s Health Advisory Council, “some patients may find that they are super responders for those who respond. [the] recommended doses and can notice weight loss and other benefits to microdose. «
But, there is not much research to support the benefits of microdosis, and for that reason, professional organizations such as the American Diabetes Association do not support microdosis. The best thing you can do is talk to your medical care provider about your dose, cost and any other restlessness you may have before making changes.
Are Microdosis Glp-1 drugs safe?
Many people who microdose in LPG-1 medications are taking a compound LPG-1, which means that the medicine was performed in a composite pharmacy and is not approved by the FDA for safety, quality or efficiency. But the lack of supervision of the FDA can make the ingredients too strong, not strong enough or even harmful to their health.
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Anyone who takes a GLP-1 medication must opt for drugs approved by the FDA when possible to know exactly what he is getting and how much he is getting. GLP-1 medications approved by the FDA come on injectable pens with a precise dose, while GLP-1 medications generally come in a vial with a syringe that can offer more flexibility for microdose, but also opens the possibilities of taking too much or very little medication. And, again, whatever in the road has not been evaluated by the FDA.
«The safety of LPG-1 microdeose medications is not well established,» Stanford said. «Potential risks include inappropriate management of diseases, unpredictable side effects and interactions with other medications.»
Do not be fooled by social networks
It is easy to get caught in what you are seeing and listening online, but it seems too good to be true, it probably is. There are illegal online pharmacies that sell GLP-1 medications and those medications are not verified by safety. In general, it is important to talk to your medical care provider before making changes or try a new medication. Microdosis may seem that it is a small thing, but it can have a great impact on your health.
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